Somatic LINE-1 retrotransposition burden

Biomarker1 paper1 finding

Humans1

Associations

1

Adjacent normal lung tissue L1 burden

upin humans1

1 study

Adjacent normal lung tissue L1 burden is associated with somatic LINE-1 retrotransposition burden in humans (ρ = 0.79, P < 10−5).
Humanswithin individuals across matched lung tumor and adjacent normal tissuelungn = 55
Whole-Genome Sequencing Reveals Somatic LINE-1 and Alu Retrotransposition Extending Beyond Lung Tumors into Adjacent Normal Tissue · Preprints.org · 28 Sep 2026 · Preprint

Adjacent normal lung tissue L1 burden →

Latest

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Preprints.orgHumansPreprint29 Sep

Whole-Genome Sequencing Reveals Somatic LINE-1 and Alu Retrotransposition Extending Beyond Lung Tumors into Adjacent Normal Tissue