Adjacent normal lung tissue L1 burden

Biomarker1 finding

Associations

1

Somatic LINE-1 retrotransposition burden

upin humans1

1 study
  1. Adjacent normal lung tissue L1 burden is associated with somatic LINE-1 retrotransposition burden in humans (ρ = 0.79, P < 10−5).

    Humanswithin individuals across matched lung tumor and adjacent normal tissuelungn = 55

    Whole-Genome Sequencing Reveals Somatic LINE-1 and Alu Retrotransposition Extending Beyond Lung Tumors into Adjacent Normal Tissue · Preprints.org · 28 Sep 2026 · Preprint

Somatic LINE-1 retrotransposition burden →