Soluble Klotho

1. Soluble Klotho is associated with systemic immune-inflammation index in humans (β = -0.08, 95% CI -0.10 to -0.05, P < 0.01).

   “high level of S-Klotho was associated with low level of SII after multivariate adjustments (β=-0.08, 95%CI:-0.10- -0.05, P < 0.01)”

   Humansn = 11,108

   Lower serum Klotho level and higher systemic immune-inflammation index: an inverse correlation

   BMC geriatrics·11 Oct 2023

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1. Dietary inflammatory index is associated with soluble Klotho in humans (β = 52.223, R2 = 0.057, p = 0.043).

   “a weak positive association was observed between DII and S-Klotho plasma levels (β = 52.223, R2 = 0.057, p = 0.043)”

   Humansn = 73

   Dietary Inflammatory Index and S-Klotho Plasma Levels in Middle-Aged Adults

   Nutrients·21 Jan 2020

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