1 paper1 finding
Cellular senescence
upin cells1
Small extracellular vesicles induce cellular senescence in cells.
“both the soluble factors and small extracellular vesicles (sEVs) are capable of transmitting paracrine senescence to nearby cells”
Cells
Cell reports25 Jun 2019
National Institute on AgingUS$283.9k
In lab-grown human fibroblasts, tiny vesicles from senescent cells prompted dividing cells to halt division and activate a DNA damage response.In lab-grown human fibroblasts, tiny vesicles from senescent cells prompted dividing cells to halt division and activate a DNA damage response.
Delivering miR-193b-3p improved muscle repair in injured mice and targeted a protein elevated in sarcopenic human tissue.Delivering miR-193b-3p improved muscle repair in injured mice and targeted a protein elevated in sarcopenic human tissue.
Vesicles from melatonin-treated stem cells targeted SRSF1 and SP1 to lower progerin and cellular prion protein in cell models.Vesicles from melatonin-treated stem cells targeted SRSF1 and SP1 to lower progerin and cellular prion protein in cell models.