Serum IGF-1

Biomarker

1 paper2 findings

  • Animals1

Interventions

1

Canine ghrh-encoding plasmid

upin dogs1no changein dogs1

1 study
  1. Canine ghrh-encoding plasmid increases serum IGF-1 in dogs.

    “post-hoc stratification revealed that dogs with low baseline IGF-1 (<90 ng/mL) showed substantial increases”

    Animalspost-hoc subgroup with baseline IGF-1 <90 ng/mLplasmid delivered by electroporationserumsingle injection180 days

    Wellness-enhancing effects of the canine growth hormone releasing hormone therapy mediated by plasmid and electroporation in healthy old dogs

    Frontiers in veterinary science15 Sep 2025

  2. Canine ghrh-encoding plasmid has no effect on serum IGF-1 in dogs.

    “While mean serum IGF-1 concentrations did not change overall”

    Animalsoverall cohort of healthy senior dogsplasmid delivered by electroporationserumsingle injection180 daysn = 30

    Wellness-enhancing effects of the canine growth hormone releasing hormone therapy mediated by plasmid and electroporation in healthy old dogs

    Frontiers in veterinary science15 Sep 2025

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