Total CD3+ T cells and naïve CD4+ and CD8+ T cell subsets

1. Canine ghrh-encoding plasmid increases total CD3+ T cells and naïve CD4+ and CD8+ T cell subsets in dogs.

   “Flow cytometry demonstrated increases in total CD3+ T cells, as well as naïve CD4+ and CD8+ T cell subsets”

   Animalshealthy senior dogsplasmid delivered by electroporationsingle injection180 daysn = 30

   Wellness-enhancing effects of the canine growth hormone releasing hormone therapy mediated by plasmid and electroporation in healthy old dogs

   Frontiers in veterinary science·15 Sep 2025

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