Senescence-like phenotype

1 paper

Cells1

Latest

11 in 12 months

The Journal of Neuroscience3 Sep

When the Brain Grows Old Too Soon: Aging and Senescence as a Driver of MS Progression

ReviewCellular senescence

bioRxiv3 Sep

Single nucleus RNA sequencing and spatial transcriptomics reveal unique functionalities of gray matter versus white matter oligodendrocytes in aging and Alzheimer's Disease

Preprint: cohort study of 48 peopleMechanisms

Cells13 Aug

Metformin Inhibits Cardiac Fibroblast Differentiation by Promoting Fatty Acid β-Oxidation: Implications for Age-Associated Cardiac Fibrosis

Experiments in cellsMetformin

Leukemia7 Aug

SLF2 and SMC5 dysfunction drives HSC aging and predisposes to MDS, defining a new inherited bone marrow failure syndrome

Experiments in human cellsBones and joints

Cellular Oncology23 Mar

Targeting senescence-like tumor-associated macrophages sensitizes chemotherapy in triple-negative breast cancer

Experiments in miceInterventions

bioRxiv14 Mar

Chronic exposure to low-concentration urban PM2.5 accelerates maladaptive repair after ischemic injury via mitochondrial dysfunction and lysosomal stress

Preprint: experiments in miceOxidative phosphorylation

Cell Death Discovery12 Mar

Targeting oncogene-induced senescence in ETV6::RUNX1 pre-leukemic cells

Experiments in miceLeukemia

International Journal of Stem Cells6 Mar

PRPS1 (p.V42L) Mutation in Arts Syndrome Induces Aberrant Neural Stem Cell Development and Neuronal Senescence-Like Phenotype: Rescue by Nicotinamide Mononucleotide Supplementation

Experiments in human cellsNicotinamide mononucleotide

Apoptosis10 Feb

Removing therapy-induced senescent cancer cells targets and potentiates the response of pancreatic cancer cells toward PARP inhibitors as maintenance therapy

Experiments in human cellsPancreatic cancer

npj Aging18 Jan

Decreased S100A7 expression is linked to altered differentiation-, autophagy- and senescence-related programs during skin aging

Experiments in human cellsAutophagy