Senescence-derived extracellular citrate

1 paper1 finding

Animals1

Upstream

1

ANKH

mediatesin human cells1

1 study

ANKH mediates senescence-derived extracellular citrate in human cells.
“EC is partially mediated by a newly described plasma membrane citrate transporter ANKH/SLC62A1 (progressive human ankylosis -ANKH) in senescent fibroblasts.”
Cellssenescent fibroblastsfibroblast
Membrane transporter progressive ankylosis protein homologue (ANKH/Ank) partially mediates senescence-derived extracellular citrate and is regulated by DNA damage, inflammation, and ageing
Frontiers in aging4 Jun 2025

Latest

Frontiers in Aging19 Jun

Membrane transporter progressive ankylosis protein homologue (ANKH/Ank) partially mediates senescence-derived extracellular citrate and is regulated by DNA damage, inflammation, and ageing

Experiments in miceDNA damage response

bioRxiv30 Aug

Membrane transporter Progressive Ankylosis Protein Homolog ( ANKH / Ank ) partially mediates senescence-derived extracellular citrate and is regulated by DNA damage, inflammation and ageing

Preprint: experiments in animalsMechanisms