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ANKH expression

Biomarker

1 paper2 findings

  • Animals1

Interventions

1

INTERLEUKIN-1 alpha

downin human cells1

1 study

  1. INTERLEUKIN-1 alpha decreases ANKH expression in human cells.

    “EC and ANKH were inhibited by interleukin 1α (IL-1α) in dividing and senescent fibroblasts”

    Cellsdividing and senescent fibroblastsfibroblast

    Membrane transporter progressive ankylosis protein homologue (ANKH/Ank) partially mediates senescence-derived extracellular citrate and is regulated by DNA damage, inflammation, and ageing

    Frontiers in aging4 Jun 2025

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Associations

1

Cellular senescence

upin human cells1

1 study

  1. Cellular senescence is associated with ANKH expression in human cells.

    “ANKH was upregulated in other senescent cell types relevant to ageing but not keratinocytes.”

    Cellsother senescent cell types, excluding keratinocytes

    Membrane transporter progressive ankylosis protein homologue (ANKH/Ank) partially mediates senescence-derived extracellular citrate and is regulated by DNA damage, inflammation, and ageing

    Frontiers in aging4 Jun 2025

More on Cellular senescence

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