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ANKH

Gene

1 paper1 finding

HGNCNCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Agencia Estatal de Investigación and 2 more
  • Animals1

Effects

1

Senescence-derived extracellular citrate

mediatesin human cells1

1 study

  1. ANKH mediates senescence-derived extracellular citrate in human cells.

    “EC is partially mediated by a newly described plasma membrane citrate transporter ANKH/SLC62A1 (progressive human ankylosis -ANKH) in senescent fibroblasts.”

    Cellssenescent fibroblastsfibroblast

    Membrane transporter progressive ankylosis protein homologue (ANKH/Ank) partially mediates senescence-derived extracellular citrate and is regulated by DNA damage, inflammation, and ageing

    Frontiers in aging4 Jun 2025

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