Experiments in mice suggested that an enzyme released by nerve cells helps compensate for age-related brain changes and preserve memory.Experiments in mice suggested that an enzyme released by nerve cells helps compensate for age-related brain changes and preserve memory.
Experiments in aged male mice, 5 weeks, against aged mice receiving control lentivirusMechanisms
Limit: Only male mice were studied; memory benefits in females remain untested
An animal experiment compared scans with brain tissue in young and older squirrel monkeys, linking an imaging measure to amyloid vessel disease and tissue injury.An animal experiment compared scans with brain tissue in young and older squirrel monkeys, linking an imaging measure to amyloid vessel disease and tissue injury.
Preprint: cross-sectional study of 23 female squirrel monkeysBiomarkers
Limit: Histological validation excluded young and early-geriatric monkeys retained for breeding