RANKL/OPG ratio

Biomarker

2 papers2 findings

  • Animals1

Interventions

1

KISSPEPTIN-10

downin mice1

1 study
  1. KISSPEPTIN-10 decreases RANKL/OPG ratio in mice.

    “In OVX mice, 1 nmol Kp10 prevented the rise in plasma RANKL/OPG ratio and the reduction in BV, BV/TV, Tb.N, and Tb.Th.”

    Animalsovariectomized miceplasma1 nmol/day30 daysfemales

    SAT-807 Kisspeptin Prevents Bone Loss Caused by the Lack of Estrogen in Ovariectomized Rodents

    ENDO 2025 abstract22 Oct 2025

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Upstream

1

Cellular senescence

upin reviews1

1 study
  1. Cellular senescence increases RANKL/OPG ratio.

    “shift toward resorptive remodeling reflected by an elevated RANKL/OPG ratio.”

    Reviewin bone cellular senescence

    Biomarkers of cellular senescence in bone tissue

    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego1 Jan 2026

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