Proinflammatory cytokine expression

2 papers1 finding

Humans1
Animals1

Upstream

1

gata4

upin cells1

1 study

gata4 increases proinflammatory cytokine expression in cells.
“overexpressing GATA4 in young chondrocytes remarkably reduced their cartilage-forming capacity in vitro and induced the upregulation of proinflammatory cytokines.”
CellsGATA4 overexpressionchondrocyte
Aging-associated Increase of GATA4 levels in Articular Cartilage is Linked to Impaired Regenerative Capacity of Chondrocytes and Osteoarthritis
eLife21 Aug 2025Preprint

Latest

1 in 12 months

Scientific Reports14 Feb

Fish (Alaska Pollock) protein intake attenuates age-related short-term memory decline through gut microbiota modulation

Experiments in miceGut and microbiome

eLife21 Aug

Aging-associated Increase of GATA4 levels in Articular Cartilage is Linked to Impaired Regenerative Capacity of Chondrocytes and Osteoarthritis

Preprint: study in peopleBones and joints

Journal of Endodontics20 Jul

Impact of Cellular Senescence on the Immune-Inflammatory Response and Regenerative Capacity of Human Dental Pulp Cells

Experiments in cellsMechanisms

Food & Function1 Jan

Nutritional targeting circulating eNAMPT attenuates NLRP3 inflammasome activation in alcoholic liver injury: therapeutic potential of nicotinamide riboside

Experiments in miceNicotinamide riboside

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Losartan attenuates sex-dependent hypertension, neuroinflammation, and cognitive impairment in the aging male sprague-dawley rat

Experiments in animalsInterventions