Aggrecan

3 papers1 finding

Animals1
Cells2

Upstream

1

gata4

downin human cells1

1 study

gata4 inhibits aggrecan in human cells.
Cellsold chondrocyteschondrocytes
Aging-associated increase of GATA4 levels in articular cartilage is linked to impaired regenerative capacity of chondrocytes and osteoarthritis
eLife12 Aug 2026

Latest

6 in 12 months

ACS Biomaterials Science & Engineering8 Sep

Synergistic Tuning of Pore Architecture and Mechanical Properties in a Biomimetic COL-HA-PVA Hydrogel Directs BMSC Chondrogenesis for Osteochondral Regeneration

Experiments in goatsInterventions

Stem Cell Reports28 Aug

CRISPR activation reveals SOX5/6/9 as key transcriptional regulators directing iPSC-derived cells toward a notochordal lineage

Experiments in human cellsInterventions

bioRxiv20 Aug

Decorin-mediated Extracellular Matrix Stabilization Maintains Cartilage Integrity During Aging

Preprint: experiments in miceExtracellular matrix

International Journal of Biological Macromolecules13 Aug

In vitro and in vivo chondrogenic performance of κ-carrageenan/silk fibroin bioinks containing ADMSCs-seeded microcarriers for auricular cartilage regeneration

Experiments in rabbitsBones and joints

eLife12 Aug

Aging-associated increase of GATA4 levels in articular cartilage is linked to impaired regenerative capacity of chondrocytes and osteoarthritis

Experiments in human cellsBones and joints

Free Radical Biology & Medicine7 Aug

FOXO3 counteracts oxidative stress-induced nucleus pulposus cell senescence via BNIP3-mediated mitophagy in intervertebral disc degeneration

Experiments in cellsIntervertebral disc degeneration