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SMAD1/5 phosphorylation

Biomarker

2 papers2 findings

  • Humans2

Upstream

1

gata4

upin cells2

2 studies

  1. gata4 increases SMAD1/5 phosphorylation in cells.

    “Mechanistically, we found that overexpressing GATA4 significantly increased the phosphorylation of SMAD1/5.”

    CellsGATA4 overexpressionchondrocyte

    Aging-associated Increase of GATA4 levels in Articular Cartilage is Linked to Impaired Regenerative Capacity of Chondrocytes and Osteoarthritis

    eLife24 Sep 2025Preprint

  2. gata4 increases SMAD1/5 phosphorylation in cells.

    “overexpressing GATA4 significantly increased the phosphorylation of SMAD1/5.”

    CellsGATA4 overexpressionchondrocyte

    Aging-associated Increase of GATA4 levels in Articular Cartilage is Linked to Impaired Regenerative Capacity of Chondrocytes and Osteoarthritis

    eLife21 Aug 2025Preprint

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