Pro-inflammatory factors

Biomarker

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6 new papers in 30 daysSee all 172

Animals4

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35 papers in 12 months

Biomolecules & TherapeuticsApr 30

Pseudoephedrine Improves Chronic Obstructive Pulmonary Disease by Regulating Airway Senescence and Mitochondrial Function through PI3K/AKT/mTOR Axis

Experiments in ratsChronic obstructive pulmonary disease

Paper

Neuroscience and Biobehavioral ReviewsSep 26

Investigating the mediating effect of myokines on exercise-induced cognitive changes in older adults: A living systematic review and meta-analysis

Meta-analysis of randomized trialsExercise

Paper

Cell MetabolismOct 24

Mechanical loading of bone extended lifespan in mice

Applying mechanical force along the shinbone extended lifespan by 9.4%, or 79.5 days, in mice aged 20–24 months.Applying mechanical force along the shinbone extended lifespan by 9.4%, or 79.5 days, in mice aged 20–24 months.

Mouse studyBones and joints

Paper

Food Science & NutritionOct 2

Gastrodia elata polysaccharide extends worm lifespan and mitigates age-related deficits in mice

The treatment reduced oxidative stress, suppressed inflammation, and remodeled the gut microbiome in naturally aging mice while prolonging survival in nematodes.The treatment reduced oxidative stress, suppressed inflammation, and remodeled the gut microbiome in naturally aging mice while prolonging survival in nematodes.

Experiments in wormsInterventions

Paper

Frontiers in Public HealthOct 2

Exercise linked to reduced epicardial fat in older adults

In a randomized trial, epicardial adipose volume fell by 15.15 mL more with exercise than in controls over 12 months.In a randomized trial, epicardial adipose volume fell by 15.15 mL more with exercise than in controls over 12 months.

Randomized trial in 156 peopleExercise

Paper

Neural Regeneration ResearchOct 2

Crosstalk between exosomes and cellular senescence: A core vicious loop promoting α-synuclein pathology in Parkinson's disease

ReviewCellular senescence

Paper

MoleculesSep 28

Baicalein reduces disuse-driven skeletal senescence and alters gut microbes in rats

Oral treatment restored bone density and mechanical strength while suppressing inflammatory markers and rebalancing intestinal bacteria in a disuse model.Oral treatment restored bone density and mechanical strength while suppressing inflammatory markers and rebalancing intestinal bacteria in a disuse model.

Experiments in ratsInterventions

Paper

International Journal of Molecular SciencesSep 28