Presynaptic active zones
1 paper studies it15 more mention it1 finding
- Model organisms1
Upstream
1dlp
downin flies1
1 study
dlp
downin flies1
dlp protects against presynaptic active zones in flies.
“Restoring Dlp expression in MBNs mitigated locomotor and working-memory alterations, and loss of presynaptic active zones.”
Model organismsin (G4C2)44X mushroom body neurons
bioRxiv : the preprint server for biologyPreprint
Latest
5 papers in 12 monthsAutophagy
Non-cell autonomous control of presynaptic remodeling by the hypothalamic autophagy-NPY axis
Experiments in fliesAutophagy
The EMBO Journal
Local autophagy impairment triggers brain-wide presynaptic remodeling and resilience
Experiments in fliesAutophagy
bioRxiv
Active zone remodeling by Bruchpilot couples synaptic architecture to Kv1/Shaker excitability control
Preprint: experiments in fliesSynapse
PLOS Biology
The Drosophila escape motor circuit shows differential vulnerability to aging linked to functional decay
Experiments in fliesMechanisms
bioRxiv
Autophagy-driven Presynaptic Reorganization as a Molecular Signature of Brain Resilience
Preprint: experiments in fliesAutophagy
Redox Biology
Coupling of mitochondrial state with active zone plasticity in early brain aging
Experiments in fliesMitochondrion
PLOS Biology
A brain-wide form of presynaptic active zone plasticity orchestrates resilience to brain aging in Drosophila
Experiments in fliesMechanisms
bioRxiv
A brain-wide form of presynaptic active zone plasticity orchestrates resilience to brain aging in Drosophila
Preprint: experiments in fliesMechanisms
Aging Cell
Mitochondrial aconitase 1 regulates age-related memory impairment via autophagy/mitophagy-mediated neural plasticity in middle-aged flies
Experiments in model organismsMechanisms