dlp

1 paper studies it1 finding

NCBI Gene Taxon

1 lab in 1 country

Funders: DOD and 1 more

Model organisms1

Effects

1

Presynaptic active zones

downin flies1

1 study

dlp protects against presynaptic active zones in flies.
“Restoring Dlp expression in MBNs mitigated locomotor and working-memory alterations, and loss of presynaptic active zones.”
Model organismsin (G4C2)44X mushroom body neurons
C9orf72 -associated G4C2 hexanucleotide repeat expression in Drosophila mushroom bodies causes age dependent TDP-43 pathology and dementia relevant phenotypes mediated in part by the glypican Dlp/GPC6
bioRxiv : the preprint server for biologyMay 12, 2026Preprint

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bioRxivMay 25

C9orf72 -associated G4C2 hexanucleotide repeat expression in Drosophila mushroom bodies causes age dependent TDP-43 pathology and dementia relevant phenotypes mediated in part by the glypican Dlp/GPC6

Preprint: experiments in fliesC9ORF72