There are 13 papers on plasma creatinine in aging research: 2 trials and 3 observational studies in people, 8 in animals.
13 papers study it37 more mention it6 findings
See all 50 papers on plasma creatinine
“Significant hHF/CV death multivariate predictors were higher age and plasma creatinine, and prior heart failure (HF), myocardial infarction (MI), atrial fibrillation (AF) and stroke.”
- Human trial2
- Humans3
- Animals8
Interventions
4Dapagliflozin
downin mice1
1 study
Dapagliflozin
downin mice1
Dapagliflozin decreases plasma creatinine in aristolochic acid-treated mice.
“Dapa also attenuated AA-induced increases in plasma creatinine”
Animalsin aristolochic acid-treated mice3 wk
SGLT2 inhibitor dapagliflozin protects the kidney in a murine model of Balkan nephropathy
American journal of physiology. Renal physiology
Senescent scattered tubular-like cells
upin mice1
1 study
Senescent scattered tubular-like cells
upin mice1
Senescent scattered tubular-like cells increase plasma creatinine in mice (compared with control (non-senescent) STCs).
“Plasma creatinine and renal tissue hypoxia increased in senescent compared with control cells.”
Animalscompared with control (non-senescent) STCssenescent (cesium-irradiated porcine STCs)5 × 10^5 cells4 weeks
Transplanted senescent renal scattered tubular-like cells induce injury in the mouse kidney
American journal of physiology. Renal physiology
Alpha-ketoglutarate + malate
no changein rats1
1 study
Alpha-ketoglutarate + malate
no changein rats1
Alpha-ketoglutarate + malate showed no clear effect on plasma creatinine in rats (I/R-induced acute kidney injury).
“Intravenous infusion of αKG/MAL at a cumulative dose of 1 mmol/kg each (146 mg/kg αKG and 134 mg/kg MAL) did not prevent I/R-induced increases in plasma creatinine”
AnimalsI/R-induced acute kidney injury1 mmol/kg eachmales
Adverse effects of α-ketoglutarate/malate in a rat model of acute kidney injury
American journal of physiology. Renal physiology
Creatine monohydrate plus conjugated linoleic acid
upin humans1
1 study
Creatine monohydrate plus conjugated linoleic acid
upin humans1
Creatine monohydrate plus conjugated linoleic acid increases plasma creatinine in humans (P<0.05).
“Plasma creatinine (P<0.05), but not creatinine clearance, increased for CrM+CLA”
Human trialsix months
PloS one
Associations
2NAMPT RS61330082 polymorphism
mixedin humans1
1 study
NAMPT RS61330082 polymorphism
mixedin humans1
NAMPT rs61330082 polymorphism is associated with plasma creatinine in humans.
“NAMPT rs61330082 polymorphism was significantly associated with the progression of hypertension grade in T2MH patients and also affected plasma creatinine and LDL-c levels”
Humans
Diabetes, metabolic syndrome and obesity : targets and therapy
Hospitalization for heart failure or cardiovascular death
upin humans1
1 study
Hospitalization for heart failure or cardiovascular death
upin humans1
Plasma creatinine raises the risk of hospitalization for heart failure or cardiovascular death in humans.
“Significant hHF/CV death multivariate predictors were higher age and plasma creatinine, and prior heart failure (HF), myocardial infarction (MI), atrial fibrillation (AF) and stroke.”
Human trialpatients with coronary heart disease and impaired glucose tolerance, multivariate Cox modelsmedian 5-year follow-up
Diabetes research and clinical practice