Frontiers in Cell and Developmental Biology
Esketamine tied to less decline after surgery at 60–80 with sleep loss
Among sleep-deprived patients, cognitive decline seven days after surgery occurred in 32.5% without esketamine and 17.7% with it.Among sleep-deprived patients, cognitive decline seven days after surgery occurred in 32.5% without esketamine and 17.7% with it.
Cohort · 398 peopleInterventions
Who was studied398 older adults undergoing elective major non-cardiac surgery
What changedEarly cognitive decline occurred in 17.7% of sleep-deprived patients receiving esketamine versus 32.5% without it
The catchAnticipated analgesic needs could influence esketamine prescribing and confound the cognitive comparison