P53 protein

Papers on P53 protein

94 papers3 new in 30 days

Thursday, October 29

Tuesday, October 27

Chemico-biological Interactions

Chemical exposure caused Parkinson’s-like changes in mice

Exposed mice developed dose-dependent movement and thinking problems, alongside signs of senescence, a state in which cells stop dividing, in brain immune cells.Exposed mice developed dose-dependent movement and thinking problems, alongside signs of senescence, a state in which cells stop dividing, in brain immune cells.

Figure from Chemico-biological Interactions
Mouse studyMechanisms

Thursday, October 22

Wednesday, October 7

Cell Death Discovery

New protein form pushed lab-grown cells to stop dividing

Cell experiments identified a previously unknown protein form that responded to DNA damage and triggered senescence, a state in which cells stop dividing.Cell experiments identified a previously unknown protein form that responded to DNA damage and triggered senescence, a state in which cells stop dividing.

Figure from Cell Death Discovery
Experiments in cellsMechanisms

Tuesday, September 22

Geromedicine

Protein variant lowered inflammation-linked gene activity in mice

Experiments in mice with premature aging and naturally aged mice found lower activity of a gene for an inflammatory signal, with four or five animals per group.Experiments in mice with premature aging and naturally aged mice found lower activity of a gene for an inflammatory signal, with four or five animals per group.

Transgenic expression of Δ133p53α is associated with lower serum IL-6 (A) and CXCL10 (B) levels in heterozygous LmnaG609G/+ progeria mice.
Mouse studyInterventions

Monday, June 22

Monday, June 1

Thursday, May 14

Friday, April 10

Monday, March 30

Thursday, March 12

Tuesday, December 16

Thursday, September 18

Monday, September 1

Thursday, August 7

Monday, August 4

Friday, July 11

Tuesday, June 17

Thursday, April 3

Saturday, February 8

Monday, August 12

Thursday, June 20

Monday, April 15

Tuesday, January 2

Wednesday, July 5

Saturday, October 29

Thursday, July 14

Tuesday, April 5

Sunday, February 13