International Journal of Cardiology·Oct 29Muscle-specific programmed cell death 5 deletion attenuates cardiac agingExperiments in miceApoptosisPaper
Iranian Journal of Basic Medical Sciences·Oct 12Telomerase activator-65 and pomegranate peel improved the health status of the liver in aged rats; multi-targets involvedExperiments in ratsInterventionsPaper
Molecules·Sep 11Chemo-Preventive Action of Resveratrol: Suppression of p53-A Molecular Targeting ApproachReviewResveratrolPaper
International Journal of Molecular Sciences·Aug 28The Changes in the p53 Protein across the Animal Kingdom Point to Its Involvement in LongevityComputational studyMechanismsPaper
Nature Communications·Aug 22O-GlcNAcylated p53 in the liver modulates hepatic glucose productionExperiments in miceTP53Paper
Cell and Tissue Research·Jul 6Estrogen prevents cellular senescence and bone loss through Usp10-dependent p53 degradation in osteocytes and osteoblasts: the role of estrogen in bone cell senescenceExperiments in miceCellular senescencePaper
Cell & Bioscience·Jun 9Spermidine induces cytoprotective autophagy of female germline stem cells in vitro and ameliorates aging caused by oxidative stress through upregulated sequestosome-1/p62 expressionExperiments in cellsSpermidinePaper
Experimental Gerontology·May 23Sargahydroquinoic acid (SHQA) suppresses cellular senescence through Akt/mTOR signaling pathwayExperiments in human cellsInterventionsPaper
Stem Cells International·Feb 20Rapamycin Treatment of Tendon Stem/Progenitor Cells Reduces Cellular Senescence by Upregulating AutophagyExperiments in rat cellsRapamycinPaper
Molecular Medicine·Dec 11High-expression of ROCK1 modulates the apoptosis of lens epithelial cells in age-related cataracts by targeting p53 geneExperiments in cellsMechanismsPaper
Iranian Journal of Basic Medical Sciences·Nov 6Effects of alpha-mangostin on memory senescence induced by high glucose in human umbilical vein endothelial cellsExperiments in human cellsInterventionsPaper
Carcinogenesis·Jul 4Targeting cellular senescence in cancer and aging: roles of p53 and its isoformsReviewCellular senescencePaper
Kidney International Reports·Jun 9Biological Efficacy and Safety of Niacinamide in Patients With ADPKDRandomized trial in 36 peopleNicotinamidePaper
Cell Death & Disease·May 14ZNF746/PARIS overexpression induces cellular senescence through FoxO1/p21 axis activation in myoblastsExperiments in cellsCellular senescencePaper
bioRxiv·May 7The changes in the p53 protein across the animal kingdom pointing to its involvement in longevityPreprint: computational studyMechanismsPaper
Scientific Reports·Apr 26Unprovoked Stabilization and Nuclear Accumulation of the Naked Mole-Rat p53 ProteinExperiments in cellsTP53Paper
Medical Science Monitor·Apr 19Effect of Aldosterone on Senescence and Proliferation Inhibition of Endothelial Progenitor Cells Induced by Sirtuin 1 (SIRT1) in Pulmonary Arterial HypertensionExperiments in 10 ratsSirtuin signalingPaper
Antiviral Research·Apr 10p53 and p53-related mediators PAI-1 and IGFBP-3 are downregulated in peripheral blood mononuclear cells of HIV-patients exposed to non-nucleoside reverse transcriptase inhibitorsCross-sectional study in peopleTP53Paper
American Journal of Translational Research·Mar 211,25-Dihydroxyvitamin D insufficiency accelerates age-related bone loss by increasing oxidative stress and cell senescenceExperiments in miceCellular senescencePaper
International Immunopharmacology·Feb 18M1 macrophages accelerate renal glomerular endothelial cell senescence through reactive oxygen species accumulation in streptozotocin-induced diabetic miceExperiments in miceCellular senescencePaper
Cell Biology International·Feb 11FAM96B inhibits the senescence of dental pulp stem cellsExperiments in human cellsCellular senescencePaper
Physiological Reports·Feb 7Contusion spinal cord injury upregulates p53 protein expression in rat soleus muscle at multiple timepoints but not key senescence cytokinesExperiments in ratsCellular senescencePaper
Cancers·Feb 6Deciphering the Molecular Mechanism of Spontaneous Senescence in Primary Epithelial Ovarian Cancer CellsExperiments in human cellsCellular senescencePaper
Biochemical and Biophysical Research Communications·Jan 25Tempo-spatial alternative polyadenylation analysis reveals that 3' UTR lengthening of Mdm2 regulates p53 expression and cellular senescence in aged rat testisExperiments in cellsCellular senescencePaper
International Journal of Molecular Sciences·Jan 19P53 and The Immune Response: 40 Years of Exploration-A Plan for the FutureReviewMechanismsPaper
Experimental and Therapeutic Medicine·Dec 5Expression of miR-34a in cataract rats and its related mechanismExperiments in 30 ratsEyePaper
Daru·Dec 4Alpha-mangostin decreased cellular senescence in human umbilical vein endothelial cellsExperiments in human cellsInterventionsPaper
Biogerontology·Oct 11IL-6 deficiency attenuates p53 protein accumulation in aged male mouse hippocampusExperiments in miceIL-6 signalingPaper