Myeloid bias

1 paper

Animals1

Latest

18 in 12 months

Research Square3 h

Short reprogramming reverses blood stem cell aging in mice

Activating reprogramming factors for 16 days in old mice reduced DNA damage, improved blood reconstitution, and dampened transposable element activity.Activating reprogramming factors for 16 days in old mice reduced DNA damage, improved blood reconstitution, and dampened transposable element activity.

Preprint: experiments in miceInterventions

International Journal of Molecular Sciences28 Sep

Why Some People Live Past 100: The Role of the Immune System in Centenarians, Semi-Supercentenarians and Supercentenarians

ReviewImmune response

Aging Cell24 Sep

The Role of EVs in the Aging Hematopoietic System

ReviewBlood and immune system

Signal Transduction and Targeted Therapy24 Sep

Targeting BIRC6 rejuvenates hematopoietic stem cell aging and immunosenescence

Experiments in miceBlood and immune system

Nature Genetics16 Sep

Type 1 interferon perturbates clonal competition by reshaping human blood development

Trial in peopleInterventions

Redox Biology15 Sep

Age-related IGF-1 decline permits a redox-sensitive transcriptional shift that directs hematopoiesis toward a CCR2⁺ myeloid fate

Experiments in animalsBlood and immune system

Transplantation and Cellular Therapy11 Sep

Integrated Analysis of Hematopoietic Changes Following Heterochronic Bone Marrow Transplantation Between Young and Aged Mice

Experiments in miceBlood and immune system

Research Square5 Sep

Endothelial RANK signaling triggers bone marrow inflammaging

Preprint: experiments in miceIL-1 signalling

Research Square4 Sep

Endothelial RANK signaling triggers bone marrow inflammaging through IL-1β expression

Preprint: experiments in miceIL-1 signalling

bioRxiv3 Sep

Neogenin-1 marks myeloid-primed fetal hematopoietic stem cells that undergo progressive lineage-restriction with age

Preprint: experiments in miceBlood and immune system