Transient reprogramming

InterventionPartial reprogramming1 paper2 findings

  • Animals1

Outcomes

2

Myeloid bias

downin mice1Very low certainty

1 study
  1. Transient reprogramming decreases myeloid bias in mice.

    Animalsphysiological and LPS-driven HSC aging

    Transient reprogramming limits AP-1-associated chromatin opening and transposable element activation to preserve hematopoietic stem cell function during aging and stress · bioRxiv · 31 Aug 2026 · Preprint

Hematopoietic reconstitution

upin mice1Very low certainty

1 study
  1. Transient reprogramming improves hematopoietic reconstitution in mice.

    Animalsphysiological and LPS-driven HSC aging

    Transient reprogramming limits AP-1-associated chromatin opening and transposable element activation to preserve hematopoietic stem cell function during aging and stress · bioRxiv · 31 Aug 2026 · Preprint

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