MechanismsAnimals
Age-related IGF-1 decline permits a redox-sensitive transcriptional shift that directs hematopoiesis toward a CCR2⁺ myeloid fate
Redox Biology
- Insulin/IGF-1 signalling
- NF-κB signalling
- Oxidative stress and ROS signalling
- CCR2
- Immunosuppression
- CCR2+ monocytes
The paper
Chen Z, Fu X, Liu C et al.
Redox Biology · 12 Sep 2026
