Reverse transcriptase inhibition

Intervention

1 paper2 findings

  • 1 lab
  • Animals1

Outcomes

2

DNA damage

downin mice1

1 study
  1. Reverse transcriptase inhibition decreases DNA damage in mice.

    Animalshematopoietic stem cell

    Short reprogramming reverses blood stem cell aging in mice

    Research Square9 Oct 2026Preprint

HSC function

upin mice1

1 study
  1. Reverse transcriptase inhibition improves HSC function in mice.

    Animalshematopoietic stem cell

    Short reprogramming reverses blood stem cell aging in mice

    Research Square9 Oct 2026Preprint

Latest

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Research Square

Short reprogramming reverses blood stem cell aging in mice

Activating reprogramming factors for 16 days in old mice reduced DNA damage, improved blood reconstitution, and dampened transposable element activity.Activating reprogramming factors for 16 days in old mice reduced DNA damage, improved blood reconstitution, and dampened transposable element activity.

Preprint: experiments in miceInterventions