Mitochondrial oxygen consumption rate

Papers on mitochondrial oxygen consumption rate

23 papers2 new in 30 days

Monday, November 2

Aging CellNov 2

Rodent safety archives flag compounds linked to better survival

In rodent pesticide studies, 27 of 154 substances were linked to survival increases of at least 10% at study termination.In rodent pesticide studies, 27 of 154 substances were linked to survival increases of at least 10% at study termination.

Experiments in rodentsInterventions

Friday, October 30

International ImmunologyOct 30

Spermidine reduces oxygen use in some immune cells from aged mice

In experiments on immune cells from aged mice, spermidine, a molecule involved in cell metabolism, reduced oxygen use in one subgroup but not another.In experiments on immune cells from aged mice, spermidine, a molecule involved in cell metabolism, reduced oxygen use in one subgroup but not another.

Immune cells above a laboratory mouse contain folded mitochondria, with fewer oxygen pairs and sparser antioxidant pieces in the larger cell.

Animal cell studySpermidine

Thursday, August 13

CellsAug 13

Metformin Inhibits Cardiac Fibroblast Differentiation by Promoting Fatty Acid β-Oxidation: Implications for Age-Associated Cardiac Fibrosis

Metformin promotes fatty acid β-oxidation in adult mouse cardiac fibroblasts.

Experiments in cellsMetformin

Friday, May 1

American Journal of Respiratory and Critical Care MedicineMay 1

A76-07 Piezo Channel-mediated Regulation of Calcium Signaling and Mitochondrial Dynamics in Aging Asthmatic Human Airway Smooth Muscle

Experiments in human cellsMitochondrial fission and fusion

Friday, February 20

PLOS OneFeb 20

Characterizing mitochondrial phenotypes and MERCS in aged human skeletal muscle myoblasts

Experiments in human cellsMitochondrion

Friday, October 24

Chemico-biological InteractionsOct 24

O304 is a mitochondrial uncoupler which extends C. elegans lifespan and induces vasorelaxation of rat mesenteric arteries

Experiments in wormsInterventions

Wednesday, November 6

MicroPublication BiologyNov 6

Mitochondrial respiratory capacity is not altered in aging rat brains with or without memory impairment

Experiments in ratsOxidative phosphorylation

Wednesday, September 25

bioRxivSep 25

Mitochondrial oxidation of the carbohydrate fuel driven by pyruvate dehydrogenase robustly enhances stemness of older and geriatric Intestinal Stem Cells

Preprint: study in peopleFatty acid β-oxidation

Saturday, August 24

Aging CellAug 24

Age-related increase of CD38 directs osteoclastogenic potential of monocytic myeloid-derived suppressor cells through mitochondrial dysfunction in male mice

Experiments in miceOxidative phosphorylation

Thursday, May 23

Frontiers in Cell and Developmental BiologyMay 23

Decreased mitochondrial respiration associates with frailty in community-dwelling older adults

Cross-sectional study of 58 peopleBiomarkers

Monday, August 14

bioRxivAug 14

Characterization and contribution of RPE senescence to Age-related macular degeneration in Tnfrsf10 knock out mice

Preprint: experiments in human cellsCellular senescence

Thursday, August 4

MetabolismAug 4

The mitochondrial NAD⁺ transporter SLC25A51 is a fasting-induced gene affecting SIRT3 functions

Experiments in miceOxidative phosphorylation

Tuesday, May 3

American Journal of Physiology Renal PhysiologyMay 3

Regulation of kidney mitochondrial function by caloric restriction

Experiments in ratsDietary restriction

Friday, February 25

Aging CellFeb 25

Scavenging mitochondrial hydrogen peroxide by peroxiredoxin 3 overexpression attenuates contractile dysfunction and muscle atrophy in a murine model of accelerated sarcopenia

Experiments in miceOxidative phosphorylation

Saturday, February 19

Nature CommunicationsFeb 19

TRPC3 shapes the ER-mitochondria Ca²⁺ transfer characterizing tumour-promoting senescence

Experiments in miceCellular senescence

Wednesday, January 6

International Journal of Molecular SciencesJan 6

Alternative Splicing Increases Sirtuin Gene Family Diversity and Modulates Their Subcellular Localization and Function

Study in peopleRNA splicing

Thursday, December 3

Biomolecules & TherapeuticsDec 3

Late Passage Cultivation Induces Aged Astrocyte Phenotypes in Rat Primary Cultured Cells

Experiments in rat cellsMechanisms

Monday, October 28

Biomolecules & TherapeuticsOct 28

Etoposide Induces Mitochondrial Dysfunction and Cellular Senescence in Primary Cultured Rat Astrocytes

Experiments in rat cellsOxidative phosphorylation

Thursday, May 16

International Journal of Molecular SciencesMay 16

A Natural mtDNA Polymorphism in Complex III Is a Modifier of Healthspan in Mice

Experiments in miceMechanisms

Thursday, November 15

AgingNov 15

Azithromycin and Roxithromycin define a new family of "senolytic" drugs that target senescent human fibroblasts

Experiments in human cellsInterventions

Saturday, June 25

Experimental GerontologyJun 25

Does p49/STRAP, a SRF-binding protein (SRFBP1), modulate cardiac mitochondrial function in aging?

Experiments in miceMitochondrion

Thursday, May 5

Experimental GerontologyMay 5

Early-onset motor impairment and increased accumulation of phosphorylated α-synuclein in the motor cortex of normal aging mice are ameliorated by coenzyme Q

Experiments in miceInterventions

Sunday, March 1

BMC NeurologyMar 1

Effect of nicotinamide mononucleotide on brain mitochondrial respiratory deficits in an Alzheimer's disease-relevant murine model

Experiments in miceNicotinamide mononucleotide