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Journal of Orthopaedic Translation

Low-intensity exercise eases age-related osteoarthritis in mice

In aged mice and cultured chondrocytes, swimming and a targeted PGC-1α-activating nanoparticle suppressed senescence and altered glycolysis to protect joints.In aged mice and cultured chondrocytes, swimming and a targeted PGC-1α-activating nanoparticle suppressed senescence and altered glycolysis to protect joints.

Experiments in miceExercise