1 paper
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
1 trialPhase 460 people
1 trialPhase 2/3111 people
Islamic Azad University, Sanandaj
1 trialPhase 220 people
1 trialPhase 1/210 people
1 trialPhase 116 people
United States Army Research Institute of Environmental Medicine
1 trialPhase 112 people
National Institute of Arthritis and Musculoskeletal and Skin DiseasesUS$331.1k
In an animal experiment, drug-carrying particles preserved bone structure and enhanced bone formation in mice whose ovaries had been removed.In an animal experiment, drug-carrying particles preserved bone structure and enhanced bone formation in mice whose ovaries had been removed.
Osteoporosis was diagnosed in 13.3% of patients prescribed drops such as latanoprost, compared with 8.9% prescribed drops such as pilocarpine.Osteoporosis was diagnosed in 13.3% of patients prescribed drops such as latanoprost, compared with 8.9% prescribed drops such as pilocarpine.
Mice lacking the enzyme MMP14 in bone-forming cells initially gained bone mass when young, but later developed severe bone loss driven by immune cells.Mice lacking the enzyme MMP14 in bone-forming cells initially gained bone mass when young, but later developed severe bone loss driven by immune cells.
Experiments in mice whose ovaries had been removed linked ceruloplasmin deficiency to higher bone mass at the tissue level.Experiments in mice whose ovaries had been removed linked ceruloplasmin deficiency to higher bone mass at the tissue level.
In a mouse model of osteoporosis, silencing a gene or inhibiting its protein reduced the activity of cells that break down bone.In a mouse model of osteoporosis, silencing a gene or inhibiting its protein reduced the activity of cells that break down bone.
A titanium surface promoted bone formation around implants and improved spongy bone structure in an experiment in rats with age-related osteoporosis.A titanium surface promoted bone formation around implants and improved spongy bone structure in an experiment in rats with age-related osteoporosis.
In ovariectomized mice, six weeks of treatment with pH-responsive puerarin nanoparticles restored trabecular bone architecture and increased bone mineral density.In ovariectomized mice, six weeks of treatment with pH-responsive puerarin nanoparticles restored trabecular bone architecture and increased bone mineral density.