METosis

1. Cordycepin decreases METosis in mice.

   “bioactive compound Cordycepin exerts protective effects by suppressing p38/ERK pathway activation and attenuating METosis.”

   Animalsin LPS and thoracic irradiation-induced combined lung injury

   Endothelial Senescence-Associated Secretory Signaling Promotes Macrophage Extracellular Traps Formation and Contributes to the Exacerbation of Combined Lung Injury

   International journal of biological sciences·20 Jul 2026

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1. CXCR2 increases METosis in mice.

   “These signals engaged macrophage CXCR2, leading to p38/ERK pathway activation and reactive oxygen species (ROS) production that contributed to METs formation (METosis).”

   Animalsin combined lung injury

   Endothelial Senescence-Associated Secretory Signaling Promotes Macrophage Extracellular Traps Formation and Contributes to the Exacerbation of Combined Lung Injury

   International journal of biological sciences·20 Jul 2026

More on CXCR2