Metabolomic profile
Biomarker1 paper
- Humans1
Latest
56Time-restricted eating slows blood vessel aging in animals
In an animal experiment, limiting daily eating hours altered gut bacteria and boosted acetic acid, easing high blood pressure and artery stiffness.In an animal experiment, limiting daily eating hours altered gut bacteria and boosted acetic acid, easing high blood pressure and artery stiffness.
More inflammatory diets linked to muscle loss in older adults
In 1,048 older adults, higher dietary inflammation scores were linked to greater odds of age-related muscle loss, with an odds ratio (a comparison of…In 1,048 older adults, higher dietary inflammation scores were linked to greater odds of age-related muscle loss, with an odds ratio (a comparison of odds) of 1.305.
Protein deficiency impaired memory in aging mice
Experiments in 15-month-old mice with reduced Nipsnap1, a protein involved in cell maintenance, found reduced gene activity linked to nerve-cell…Experiments in 15-month-old mice with reduced Nipsnap1, a protein involved in cell maintenance, found reduced gene activity linked to nerve-cell signalling and increased activity linked to inflammation.
NMR metabolomics improves prediction of cardiometabolic diseases
In 54,933 healthcare system participants, profiling 250 NMR biomarkers enhanced standard risk prediction for type 2 diabetes, kidney disease, and…In 54,933 healthcare system participants, profiling 250 NMR biomarkers enhanced standard risk prediction for type 2 diabetes, kidney disease, and liver disease.
Plasma proteins link to metabolomic aging and disease risk
In over 400,000 UK Biobank participants, an NMR metabolomic aging score tracked mortality and pinpointed six candidate causal plasma proteins across…In over 400,000 UK Biobank participants, an NMR metabolomic aging score tracked mortality and pinpointed six candidate causal plasma proteins across adulthood.
Six blood metabolites distinguish metabolic health in obesity
A combined clinical-metabolomic model discriminated healthy from unhealthy obesity with an AUC of 0.78, compared with 0.69 for clinical variables…A combined clinical-metabolomic model discriminated healthy from unhealthy obesity with an AUC of 0.78, compared with 0.69 for clinical variables alone.
Plasma metabolites link to T-cell senescence in elderly COVID-19
In elderly COVID-19 patients, altered phospholipid and bile acid metabolites tracked with T-cell senescence, inflammatory cytokines, and 180-day…In elderly COVID-19 patients, altered phospholipid and bile acid metabolites tracked with T-cell senescence, inflammatory cytokines, and 180-day mortality.