Weight gain

1. Weight gain raises the risk of colon cancer in humans (HR 1.07, 95% CI 1.02-1.13).

   “In males with a body mass index (BMI) range of 18-30 kg/m2, both a weight gain of 5-20% (HR 1.07, P > z 0.01 [95% CI 1.02-1.13])”

   Humansin males with BMI 18-30 kg/m2males

   Age and sex differences in the relationship of body weight changes with colon cancer risks: A nationwide cohort study

   Scientific reports·3 Jan 2025

More on Colon cancer

1. Weight gain raises the risk of coronary heart disease mortality in humans (RR 2.01, 95% CI 1.36 to 2.97).

   “For coronary heart disease mortality, relative risks were 1.75 (1.26 to 2.43), 1.43 (1.05 to 1.93), 1.28 (0.91 to 1.80), and 2.01 (1.36 to 2.97), respectively.”

   Humansmalesn = 11,703

   Change in body weight and longevity

   JAMA·21 Oct 1992

1. Weight gain raises the risk of mortality in humans (RR 1.36, 95% CI 1.11 to 1.66).

   “and gaining more than 5 kg were 1.57 (95% confidence interval, 1.34 to 1.84), 1.26 (1.10 to 1.46), 1.06 (0.90 to 1.24), and 1.36 (1.11 to 1.66), respectively.”

   Humansmalesn = 11,703

   Change in body weight and longevity

   JAMA·21 Oct 1992