MAPT aggregation

1. Aerobic exercise decreases MAPT aggregation in mice.

   “AE restored the levels of CHMP4B, which reversed autophagy-lysosomal defects and reduced MAPT aggregation.”

   AnimalsMAPT P301L micetreadmill running8-week

   Aerobic Exercise Attenuates Autophagy-Lysosomal Flux Deficits via β2-AR-Mediated ESCRT-III Subunit CHMP4B in Mice With Human MAPT P301L

   Aging cell·26 Jul 2025

More on Aerobic exercise