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CHMP4B

Gene

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Center of Innovation Program and others
  • Cells1

Effects

1

Cellular senescence

downin human cells1

1 study

  1. CHMP4B decreases cellular senescence in human cells.

    “Transient upregulation of ESCRT-III (CHMP4B) suppressed PMD-dependent senescence.”

    Cellsplasma membrane damage

    Plasma membrane damage limits replicative lifespan in yeast and induces premature senescence in human fibroblasts

    Nature aging22 Feb 2024

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