LAMP1

2 papers

Humans2

Latest

13 in 12 months

Frontiers in Aging14 Oct

Impaired autophagy and lysosome function in human fibroblast aging

Experiments in human cellsAutophagy

Metabolic Brain Disease13 Sep

Dihydromyricetin ameliorates cognitive dysfunction in SAMP8 mice via autophagy-mediated degradation of the NLRP3 inflammasome

Experiments in miceInterventions

Environment International29 Aug

A novel dual-pathway AhR mechanism underpins cardiac senescence induced by 6PPDQ

Experiments in rat cellsCellular senescence

Frontiers in Immunology22 Aug

The auditory nerve glial transition zone is a focal site of age-related immune-myelin interactions

Experiments in miceImmune response

Autophagy16 Aug

Sequalae and reversal of age-dependent alterations in mitochondrial dynamics via autophagy enhancement in reprogrammed human neurons

Experiments in human cellsMitochondrial fission and fusion

Aging Cell29 Jul

Progerin Hinders Autophagy Flux at Its Final Stages in Hutchinson-Gilford Progeria Syndrome Cells, Preventing Its Own Autophagic Degradation

Experiments in human cellsProgeria

bioRxiv29 Jul

NPC1 deficiency engages a lysosome-genome-immune program linked to neurodegeneration and cellular aging signatures

Preprint: experiments in miceNeurodegenerative disease

Journal of Immunology Research2 Jun

Associations Between Immune Senescence and Immune Reconstitution Among People Living With HIV Undergoing Antiretroviral Therapy

Cohort study of 510 peopleCellular senescence

Autophagy25 May

NMN/NAD⁺ enhances SIRT2-modulated microtubule dynamics to improve mitochondrial and mitophagy functions in senescent cells

Experiments in human cellsNicotinamide mononucleotide

Autophagy20 May

FGF21 rejuvenates aged human adipose-derived mesenchymal stem cells via enhancement of TFE3-mediated autophagy flux

Experiments in ratsInterventions