2 papers1 finding
Icariin
upin mice1
Icariin increases Lactobacillus in mice (4.1-fold).
“aged females showed Lactobacillus enrichment (4.1-fold)”
Animals100 mg/kg/day15 daysfemales
Sex-Dimorphic Gut Microbiota Modulation by Icariin in Older Mice
GSA 2025 abstract31 Dec 2025
In a prospective study of postmenopausal women, 12 weeks of vaginal estrogen shifted urinary bacterial communities towards those seen in women without tissue thinning or…In a prospective study of postmenopausal women, 12 weeks of vaginal estrogen shifted urinary bacterial communities towards those seen in women without tissue thinning or symptoms.
In a preprint comparing women across menopausal stages, at least six weeks of vaginal estrogen tracked with more lactobacilli and fewer opportunistic pathogens.In a preprint comparing women across menopausal stages, at least six weeks of vaginal estrogen tracked with more lactobacilli and fewer opportunistic pathogens.
The treatment reduced oxidative stress, suppressed inflammation, and remodeled the gut microbiome in naturally aging mice while prolonging survival in nematodes.The treatment reduced oxidative stress, suppressed inflammation, and remodeled the gut microbiome in naturally aging mice while prolonging survival in nematodes.