Re-feeding
Re-feeding has been studied in 3 papers since 2016: none in people yet, 3 in animals. The research so far is in animals. The newest paper, Oct 7, 2024: “Impact of dietary restriction on development, mating, and reproduction in the natural predator Pardosa pseudoannulata”.
3 papers study it3 findingsUpdated
- 3 independent labs in 3 countries
- Funders: Alnylam Pharmaceuticals and others
- Animals2
- Model organisms1
What did studies of Re-feeding find?
3Studies of Re-feeding measured 3 outcomes; the most studied are cannibalism rate (1 study), monocytosis (1) and heat shock response and chaperones (1).
Cannibalism rate
downin P. pseudoannulata1
1 study
Cannibalism rate
downin P. pseudoannulata1
Re-feeding decreases cannibalism rate in P. pseudoannulata.
“It was also observed that re-feeding reduced cannibalism rates”
Model organisms
Bulletin of entomological research
Monocytosis
upin mice1
1 study
Monocytosis
upin mice1
Re-feeding induces monocytosis in mice.
“re-feeding prompted mobilization culminating in monocytosis of chronologically older and transcriptionally distinct monocytes”
Animalsafter fasting
Monocytes re-enter the bone marrow during fasting and alter the host response to infection
Immunity
Heat shock response and chaperones
upin rats1
1 study
Heat shock response and chaperones
upin rats1
Re-feeding increases heat shock response and chaperones in rats.
“Following re-feeding, levels of HSPs nearly reached ad libitum levels.”
Animalsafter restrictionliver
Aging