IL-6 production

2 papers study it24 more mention it2 findings

Animals1
Cells1

Upstream

2

MIR350

downin mouse cells1

1 study

MIR350 decreases IL-6 production in mouse cells.
“although LPS induces less IL-6 production by aged macrophages than by young macrophages, the aged cell response is rescued by production miR-350-3p inhibition.”
CellsLPS-stimulated macrophages; shown by miR-350-3p inhibitionmacrophage
miR-350-3p Contributes to Age-Associated Impairment of IL-6 Production by Macrophages
Immunological investigationsSep 27, 2018

MIR142

downin mouse cells1

1 study

MIR142 decreases IL-6 production in mouse cells.
“increased miR-142-3p expression by more than 3-fold in LPS-treated macrophages from aged mice compared with young mice, which in turn suppressed LPS-stimulated IL-6 production”
CellsLPS stimulation following trichostatin A treatmentmacrophage
Downregulated expression of miR-142-3p in macrophages contributes to increased IL-6 levels in aged mice
Molecular immunologyOct 24, 2016

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