Papers on HER-2

7,999 papers389 new in 30 days

Wednesday, November 4

PLOS OneNov 4

Treadmill prehabilitation attenuates jejunal inflammation and enhances cytoprotective protein expression in murine gut ischemia–reperfusion

Experiments in animalsInterventions

Paper

Mechanisms of Ageing and DevelopmentNov 4

Free-floating DNA levels differed across human age groups

In a cross-sectional study of 418 people aged 7–95, free-floating DNA levels increased across ages 7–80 but were lower at 81–95 than at 61–80.In a cross-sectional study of 418 people aged 7–95, free-floating DNA levels increased across ages 7–80 but were lower at 81–95 than at 61–80.

Figure from Mechanisms of Ageing and Development

Cross-sectional · 418 peopleMechanisms

Paper

TouchREVIEWS in EndocrinologyNov 4

Disease-modifying approach to cardiovascular-kidney-metabolic syndrome: The role of combining GLP-1RAs and SGLT-2is

ReviewCardiovascular-kidney-metabolic syndrome

Paper

International Journal of Molecular SciencesNov 4

Metabolic Rewiring by Pomegranate Juice and Punicalagin Is Associated with NHR-49/MDT-15-Related Responses and Enhanced Stress Resilience

Figure from International Journal of Molecular Sciences

Experiments in wormsInterventions

Paper

International Journal of Molecular SciencesNov 4

Association Between Ambient PM2.5 Exposure and Leukocyte Telomere Length Among Rural Adults: Cross-Sectional Study in Northern Thailand

Cross-sectional study of 179 peoplePopulations

Paper

Scientific ReportsNov 4

Factors associated with TyG-BMI among pre-frail older adults: a cross-sectional study using multiple linear regression and decision tree analysis

Cross-sectional study of 2,249 peoplePopulations

Paper

GeneticsNov 4

A nerve signal helps protect aging neurons in worms

In worm experiments, increasing a nerve-signaling molecule reduced excessive branching in aging sensory neurons without extending lifespan.In worm experiments, increasing a nerve-signaling molecule reduced excessive branching in aging sensory neurons without extending lifespan.

A dark blue-green worm has sparse neuron branches beside a gray worm with excessive branches, with a nerve cell and signaling fragments between them.

Worm studyMechanisms

Paper

BMC NeurologyNov 4

Mechanical thrombectomy in nonagenarians: real-world outcomes from a highly selected cohort treated at a comprehensive stroke center

Study flowchart illustrating patient selection for the nonagenarian and younger comparator cohorts

Cohort study of 100 peopleStroke

Paper

PsyArXivNov 4

Anxiety symptoms linked to hot flash severity around menopause

Two observational studies of 227 and 116 women linked anxiety-specific symptoms, but not depression-specific symptoms, to hot flash severity after accounting for general…Two observational studies of 227 and 116 women linked anxiety-specific symptoms, but not depression-specific symptoms, to hot flash severity after accounting for general distress.

Upright women in dark blue-green have dense heat ripples and chest flutters, while nearby gray women have fewer ripples and flutters.

Preprint: cross-sectional study of 227 peopleAnxiety symptoms

Paper

Research SquareNov 4

GLP-1 Receptor agonist use and attempted access in individuals with and without lifetime eating disorders: The role of diagnostic history, BMI, and medication motivation

Forest plots of odds ratios for GLP-1RA prescriptions comparing each ED group with the control group from single-diagnosis models including each ED, sex, age, and GLP‑1RA prescription for T2D…

Preprint: cross-sectional study of 5,882 peopleEating disorder

Paper

Spine OpenNov 4

Preoperative SGLT2 Inhibitor Use Is Associated With Reduced 90-Day Complications and Lower Prolonged Opioid Use After Posterior Lumbar Fusion

Cohort study of 6,200 peoplePopulations

Paper

Tuesday, November 3

DrugsNov 3

Safety and Tolerability of Sodium-Glucose Cotransporter-2 Inhibitors: A State-of-the-Art Narrative Review

ReviewSGLT2 inhibitors

Paper

Journal of the National Cancer InstituteNov 3

Translating absolute risk of breast cancer into screening frequency: a framework to guide practice

Computational studyBreast cancer

Paper

iScienceNov 3

Calcium channel links radiation to salivary gland problems in mice

Mice lacking the channel resisted early salivary gland dysfunction after irradiation; the authors linked its effects to cells entering a nondividing state.Mice lacking the channel resisted early salivary gland dysfunction after irradiation; the authors linked its effects to cells entering a nondividing state.

Mouse studyMechanisms

Paper

Journal of Pharmaceutical Health Care and SciencesNov 3

Intensive pharmacist-led guideline-directed medical therapy for hospitalized heart failure patients: a single-center retrospective cohort study

Example of a GDMT checklist (primarily for HFrEF).

Cohort study of 103 peopleHeart failure

Paper

Journal of Controlled ReleaseNov 3

Drug-filled particles reduced liver fat buildup in mice

An experiment tested navitoclax in mice with diet-induced liver disease; the packaged drug also reduced a disease activity score and scarring-related profiles.An experiment tested navitoclax in mice with diet-induced liver disease; the packaged drug also reduced a disease activity score and scarring-related profiles.