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Framingham 30-year risk of cardiovascular disease

Biomarker

1 paper2 findings

  • Humans1

Interventions

1

Perinatal HIV exposure without infection

upin humans1

1 study

  1. Perinatal HIV exposure without infection increases Framingham 30-year risk of cardiovascular disease in humans (9.7% vs. 5.8%).

    “These differences conferred a higher metabolic comorbidity score (1.5±1.4 vs. 0.3±0.7, P<0.001) and 30-year CVD risk (9.7% vs. 5.8%, P=0.02).”

    Humansmatched controls

    MON-696 Obesity and Metabolic Comorbidities in Young Adults with Perinatal HIV Exposure Without Infection

    ENDO 2025 abstract22 Oct 2025

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Associations

1

CD4+ count

downin humans1

1 study

  1. CD4+ count is associated with Framingham 30-year risk of cardiovascular disease in humans (ρ=-0.42).

    “lower maternal prenatal CD4 count was associated with higher adult CVD risk (ρ=-0.42, P=0.03).”

    Humansin the PHEU groupn = 41

    MON-696 Obesity and Metabolic Comorbidities in Young Adults with Perinatal HIV Exposure Without Infection

    ENDO 2025 abstract22 Oct 2025

More on CD4+ count

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