Fe2+/Fe3+ ratio

Biomarker1 paper1 finding

  • Model organisms1

Interventions

1

Erastin

upin flies1

1 study

  1. Erastin increases Fe2+/Fe3+ ratio in flies.

    Model organismsmales

    Fruit flies provide an in vivo model to study ferroptosis and lifespan · Redox biology · 28 Sep 2026

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Redox BiologyModel organisms

Fruit flies provide an in vivo model to study ferroptosis and lifespan

Ferroptosis-inducing compounds shortened fly lifespan in a diet-dependent manner, while antioxidant treatment restored longevity and reversed…Ferroptosis-inducing compounds shortened fly lifespan in a diet-dependent manner, while antioxidant treatment restored longevity and reversed iron-related changes in males.

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