Journal of Muscle Research and Cell Motility
CD36 regulates myogenic differentiation via chronic integrated stress response - implications for muscle aging
Experiments in mouse cellsIntegrated stress response
Papers on Factor 4
140 papers6 new in 30 days
Thursday, January 22
Thursday, January 1
Nature Communications
Phosphoproteomics of aged insulin-resistant bone identifies P70S6K phosphorylation of AFF4 as a gene-specific transcriptional regulator
Experiments in miceBones and joints
Tuesday, December 30
Preprints.org
Enhanced Cognitive Function in the Latino Population: The Familism and Lifestyle
Preprint: study in peoplePopulations
Wednesday, December 24
AAIC 2025 Abstract
Global multi‐omics analysis of brain‐targeting exerkines in progressive treadmill‐exercised rodents
Experiments in ratsTreadmill exercise
Saturday, December 20
Physiological Reports
Dietary methionine depletion and hydrogen sulfide-producing genes in perivascular adipose tissue of male Wistar rats
Experiments in ratsInterventions
Thursday, December 4
Blood
Platelet factor 4 regulates hematopoietic stem cell aging
Experiments in miceBlood and immune system
Wednesday, November 26
Wednesday, October 15
Scientific Reports
Glucosamine mitigates hyperglycemic-induced oxidative stress via the SIRT1 pathway in human corneal epithelial cells
Experiments in human cellsHyperglycemia
Monday, October 13
Journal of Diabetes and Metabolic Disorders
Amino acid metabolic signatures of dynapenic obesity in older adults: a (principal component analysis) PCA-based sex-stratified analysis in the Bushehr elderly health program
Cross-sectional study of 1,928 peopleDynapenia
Monday, October 6
Frontiers in Aging Neuroscience
Association between cardiovascular disease risk, regional brain age gap, and cognition in healthy adults
Cross-sectional study of 187 peopleCardiovascular disease
Sunday, August 31
Thursday, August 28
Cell Communication and Signaling
Senescent fibroblasts secrete CTHRC1 to promote cancer stemness in hepatocellular carcinoma
Experiments in miceCellular senescence
Thursday, August 21
World Journal of Diabetes
Rheb1 as a novel β-cell regulator connecting mTORC1, AMPK, and NOTCH1 pathways for efficient diabetes therapy
CommentaryAMPK signaling
Saturday, August 2
Experimental Neurology
Research progress on platelet factor 4 in improving cognition
ReviewInterventions
Tuesday, July 15
Saturday, July 12
Molecular and Cellular Biochemistry
ATF-4 deficiency increases ER stress and induces osteoarthritis formation in mice
Experiments in miceER unfolded protein response
Monday, April 7
Biomolecules & Biomedicine
PF4 in rejuvenation therapy: Neuroprotection and cognitive enhancement
ReviewInterventions
Friday, February 28
Alzheimer's & Dementia
Predictive value and weight of factors associated with cognitive performance in Hispanics/Latinos enrolled in the Health and Aging Brain Study: Health Disparities
Cohort study of 952 peoplePopulations
Monday, December 9
bioRxiv
Platelet Factor 4 (PF4) Regulates Hematopoietic Stem Cell Aging
Preprint: experiments in miceBlood and immune system
Tuesday, December 3
Journal of Nanobiotechnology
Engineering extracellular vesicles to transiently permeabilize the blood-brain barrier
Study in peopleInterventions
Friday, November 29
Thursday, November 28
Reproductive Toxicology
Nicotinamide mononucleotide enhances the developmental potential of mouse early embryos exposed to perfluorooctanoic acid
Experiments in mouse cellsNicotinamide mononucleotide
Friday, November 1
Molecular Cell
Senescence suppresses the integrated stress response and activates a stress-remodeled secretory phenotype
Experiments in human cellsIntegrated stress response
Saturday, September 28
Biology
Melatonin Augments the Expression of Core Transcription Factors in Aged and Alzheimer's Patient Skin Fibroblasts
Experiments in human cellsMelatonin
Wednesday, September 11
Science Translational Medicine
Targeted partial reprogramming of age-associated cell states improves markers of health in mouse models of aging
Experiments in micePartial reprogramming
Thursday, August 15
Heliyon
The disparity of platelet factor 4 and platelets in individuals of different ages
Cross-sectional study in peopleMechanisms
Tuesday, July 16
Journal of Cachexia, Sarcopenia and Muscle
Proteomic profiling of human plasma extracellular vesicles identifies PF4 and C1R as novel biomarker in sarcopenia
Case-control study in peopleSarcopenia
Saturday, July 6
Advanced Science
Short-Term Statin Therapy Induces Hepatic Insulin Resistance Through HNF4α/PAQR9/PPM1α Axis Regulated AKT Phosphorylation
Experiments in miceStatins
Tuesday, July 2
Journal of Translational Medicine
Senescent endothelial cells promote liver metastasis of uveal melanoma in single-cell resolution
Study of 11 peopleCellular senescence