Endothelium-dependent dilatation

Biomarker

2 papers study it38 more mention it1 finding

  • Animals2

Interventions

1

3,3-dimethyl-1-butanol

upin mice1

1 study
  1. 3,3-dimethyl-1-butanol improves endothelium-dependent dilatation in mice.

    “Endothelial function [carotid artery endothelium-dependent dilatation (EDD) to acetylcholine; pressure myography] progressively declined with age in control mice, which was fully prevented by DMB”

    Animalsinitiated at midlife (18 months)carotid artery1% in drinking water

    Initiation of 3,3-dimethyl-1-butanol at midlife prevents endothelial dysfunction and attenuates in vivo aortic stiffening with ageing in mice

    The Journal of physiology

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