Aortic pulse wave velocity

Biomarker

5 papers5 findings

  • Human trial1
  • Humans3
  • Animals1

Interventions

2

Aerobic exercise

downin humans1

1 study
  1. Aerobic exercise decreases aortic pulse wave velocity in humans (8.47 ± 1.40 vs 8.01 ± 1.06 m/s).

    “HR-targeted training was associated with decreased aortic pulse wave velocity (8.47 ± 1.40 vs 8.01 ± 1.06 m/s; P = .005)”

    Human trialin metabolic syndrome subjects8-weekn = 84

    Aerobic Training Effect on Arterial Stiffness in Metabolic Syndrome

    The American journal of medicine31 Aug 2017

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Spermidine

downin mice1

1 study
  1. Spermidine decreases aortic pulse wave velocity in mice.

    “Spermidine supplementation normalized aPWV, restored NO-mediated EDD and reduced nitrotyrosine, superoxide, AGEs and collagen in O.”

    Animalsagingartery

    The autophagy enhancer spermidine reverses arterial aging

    Mechanisms of ageing and development20 Apr 2013

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Associations

3

Atrial fibrillation incidence

upin humans1

1 study
  1. Aortic pulse wave velocity is associated with atrial fibrillation incidence in humans.

    “Lower DC and higher PWV were associated with higher AF incidence only after adjustment for the CHARGE-AF risk-score variables excepting height, weight, and systolic and diastolic blood pressure.”

    HumansHigher pulse wave velocity; association only after adjustment excluding height, weight, and systolic and diastolic blood pressure from CHARGE-AF variables

    Carotid Intima-Media Thickness and Arterial Stiffness and the Risk of Atrial Fibrillation: The Atherosclerosis Risk in Communities (ARIC) Study, Multi-Ethnic Study of Atherosclerosis (MESA), and the Rotterdam Study

    Journal of the American Heart Association20 May 2016

Hypertension

upin humans1

1 study
  1. Hypertension is associated with aortic pulse wave velocity in humans (8.7+/-2.3 vs 10.2+/-2.5 m/s).

    “Mean AoPWV was 8.7+/-2.3 m/s in the RVG and 10.2+/-2.5 m/s in the hypertension-diabetes group (P<0.0001).”

    Humansn = 455

    Reference values of aortic pulse wave velocity in the elderly

    Journal of hypertension1 Nov 2008

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Measurement reproducibility

upin humans1

1 study
  1. Aortic pulse wave velocity is associated with measurement reproducibility in humans (Overall reliability coefficient rI = 0.77).

    “The overall reliability coefficient was rI = 0.77.”

    HumansMeasurements collected by two sonographers and read by two readersaortan = 14

    Measurement variation of aortic pulse wave velocity in the elderly

    American journal of hypertension1 May 2001

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