DNA oxidative damage

5 papers3 findings

Humans1
Animals4

Interventions

3

Citrus unshiu

downin mice1

1 study

Citrus unshiu decreases DNA oxidative damage in mice.
“The level of DNA oxidative damage was significantly lower in the cerebral cortex of mice that ingested β-CRX and mandarin than control mice.”
Animalsin senescence-accelerated mice (SAMP10)cerebral cortex3.8-38.0%
Beta-cryptoxanthin, plentiful in Japanese mandarin orange, prevents age-related cognitive dysfunction and oxidative damage in senescence-accelerated mouse brain
Biological & pharmaceutical bulletin1 Jan 2011

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Beta-cryptoxanthin

downin mice1

1 study

Beta-cryptoxanthin decreases DNA oxidative damage in mice.
“The level of DNA oxidative damage was significantly lower in the cerebral cortex of mice that ingested β-CRX and mandarin than control mice.”
Animalsin senescence-accelerated mice (SAMP10)cerebral cortex0.5-5.0 μg/ml
Beta-cryptoxanthin, plentiful in Japanese mandarin orange, prevents age-related cognitive dysfunction and oxidative damage in senescence-accelerated mouse brain
Biological & pharmaceutical bulletin1 Jan 2011

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Green tea catechins

downin mice1

1 study

Green tea catechins prevent DNA oxidative damage in mice.
“daily consumption of GT-catechin prevented memory regression and DNA oxidative damage in these mice”
AnimalsSAMP10 micewater containing 0.02% GT-catechin35 mg/kg/day
Daily consumption of green tea catechin delays memory regression in aged mice
Biogerontology7 Sep 2006

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Latest

Frontiers in Cell and Developmental Biology5 Feb

Placental trophoblast aging in advanced maternal age is related to increased oxidative damage and decreased YAP

Cohort study in peopleMechanisms

Free Radical Biology & Medicine19 Jun

STING1-accelerated vascular smooth muscle cell senescence-associated vascular calcification in diabetes is ameliorated by oleoylethanolamide via improved mitochondrial DNA oxidative damage

Experiments in animalsInterventions

Neurobiology of Learning and Memory10 Feb

Long-term calorie restriction prevented memory impairment in middle-aged male mice and increased a marker of DNA oxidative stress in hippocampal dentate gyrus

Experiments in miceDietary restriction

DNA Repair29 Jun

Frailty, sex, and poverty are associated with DNA damage and repair in frail, middle-aged urban adults

Cross-sectional study in peopleDNA damage response

Research Square26 Oct

Altered DNA repair related proteins in Parkinson’s disease model VMAT2 Lo mice

Preprint: experiments in animalsMechanisms

Biological & Pharmaceutical Bulletin1 Jan

Beta-cryptoxanthin, plentiful in Japanese mandarin orange, prevents age-related cognitive dysfunction and oxidative damage in senescence-accelerated mouse brain

Experiments in miceInterventions

PNAS17 Feb

Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat

Experiments in naked mole-ratsOxidative stress and ROS signalling

Mechanisms of Ageing and Development7 Nov

Life-long vitamin C supplementation in combination with cold exposure does not affect oxidative damage or lifespan in mice, but decreases expression of antioxidant protection genes

Experiments in miceInterventions

Biogerontology7 Sep

Daily consumption of green tea catechin delays memory regression in aged mice

Experiments in miceInterventions

Experimental Gerontology1 Sep

Royal Jelly prolongs the life span of C3H/HeJ mice: correlation with reduced DNA damage

Experiments in miceInterventions