Citrus unshiu

1. Citrus unshiu extends lifespan in mice.

   “mice that ingested β-CRX (>1.5 μg/ml) and mandarin (>11.3%) exhibited a higher survival when 12 month-old, the presenile age of SAMP10, than control mice.”

   Animalsin senescence-accelerated mice (SAMP10)>11.3%

   Beta-cryptoxanthin, plentiful in Japanese mandarin orange, prevents age-related cognitive dysfunction and oxidative damage in senescence-accelerated mouse brain

   Biological & pharmaceutical bulletin·1 Jan 2011

1. Citrus unshiu decreases DNA oxidative damage in mice.

   “The level of DNA oxidative damage was significantly lower in the cerebral cortex of mice that ingested β-CRX and mandarin than control mice.”

   Animalsin senescence-accelerated mice (SAMP10)cerebral cortex3.8-38.0%

   Beta-cryptoxanthin, plentiful in Japanese mandarin orange, prevents age-related cognitive dysfunction and oxidative damage in senescence-accelerated mouse brain

   Biological & pharmaceutical bulletin·1 Jan 2011

More on DNA oxidative damage