Disease-associated microglia

1. CSF1R antagonist has no effect on disease-associated microglia in mice.

   “The age-related expansion of DAM was unaffected by pharmacological depletion and repopulation of microglia with a CSF1R antagonist”

   Animalsage-related expansion in micewhite matter

   Influenza A infection accelerates disease-associated microglia formation during physiological aging

   bioRxiv : the preprint server for biology·14 Dec 2025Preprint

More on CSF1R antagonist

1. Influenza a virus increases disease-associated microglia in mice.

   “In response to IAV pneumonia, DAM expanded in middle-aged mice”

   Animalsduring IAV infection and recoverywhite mattermales

   Influenza A infection accelerates disease-associated microglia formation during physiological aging

   bioRxiv : the preprint server for biology·14 Dec 2025Preprint

More on Influenza a virus

1. Disease-associated microglia is associated with glio-inflammation in humans.

   “we synthesize recent conceptual and experimental advances in neuroscience, highlighting selected studies that delineate the roles of reactive microglia and astrocytes in the contexts of developmental inflammatory stress, neurodegenerative diseases, and cellular senescence.”

   Review

   Glioinflammation: disease-associated microglia and astrocytes in psychiatric disorders, neurodegeneration, and senescence

   Frontiers in cellular neuroscience·17 Feb 2026