Influenza a virus

Exposure

2 papers2 findings

MeSH D009980

  • 1 lab in 1 country
  • Funders: Karen Toffler Charitable Trust and 1 more
  • Humans1
  • Animals1

Outcomes

2

Cellular senescence

upin mice1

1 study
  1. Influenza a virus induces cellular senescence in mice.

    “IAV pneumonia induced a transient immunosenescent-like response in microglia, marked by glucocorticoid-responsive gene expression and Ccnd3 upregulation.”

    Animalsnon-neuroinvasive IAV pneumoniamicrogliamales

    Influenza A infection accelerates disease-associated microglia formation during physiological aging

    bioRxiv : the preprint server for biology14 Dec 2025Preprint

More on Cellular senescence

Disease-associated microglia

upin mice1

1 study
  1. Influenza a virus increases disease-associated microglia in mice.

    “In response to IAV pneumonia, DAM expanded in middle-aged mice”

    Animalsduring IAV infection and recoverywhite mattermales

    Influenza A infection accelerates disease-associated microglia formation during physiological aging

    bioRxiv : the preprint server for biology14 Dec 2025Preprint

More on Disease-associated microglia

Funding

1 grant since 2023

National Institute of Allergy and Infectious DiseasesUS$419.4k

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