Collagen 1

3 papers2 findings

Animals1
Cells2

Interventions

1

Hsa-mirvana MIR-146A inhibitor

downin human cells1

1 study

Hsa-mirvana MIR-146A inhibitor decreases collagen 1 in human cells.
“downregulation of miR-146a results in a reduction of cellular proliferation, Collagen-1 production”
Cellsin NHDFsskin
miR-146a is a critical target associated with multiple biological pathways of skin aging
Frontiers in physiology29 Feb 2024

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Upstream

1

Cellular senescence

upin human cells1

1 study

Cellular senescence increases collagen 1 in human cells.
“senescent human airway epithelial cells induced fibrosis biomarkers collagen1, collagen 3, and alpha-smooth-muscle actin in target human primary lung fibroblasts.”
Cellsirradiated human airway epithelial cellslung fibroblasts
Radiation-induced Lung Injury (RILI) in Non-human Primates (NHPs) Induces Cellular Senescence and Upregulation of Tyrosine Kinase Fgr, which is Detectable in Bronchoalveolar Lavage
Radiation research1 Aug 2025

More on Cellular senescence

Latest

3 in 12 months

bioRxiv17 Jul

Cell-type-specific ATF6α programs regulate epithelial mitochondrial homeostasis and pericyte remodeling during physiological and exposure-accelerated lung aging

Preprint: experiments in miceExtracellular matrix remodelling

Archives of Oral Biology8 Dec

Inhibition of protein kinase C activity enables mineralization of senescent dental follicle cells with almost no osteogenic differentiation potential

Experiments in human cellsCellular senescence

GeroScience7 Nov

Angiotensin II induces sex-specific ventricular remodeling in aging C57Bl/6 mice

Experiments in miceRenin–angiotensin system

Radiation Research1 Aug

Radiation-induced Lung Injury (RILI) in Non-human Primates (NHPs) Induces Cellular Senescence and Upregulation of Tyrosine Kinase Fgr, which is Detectable in Bronchoalveolar Lavage

Experiments in non-human primatesCellular senescence

Aging and Disease10 Dec

Aging Deteriorates Blood Brain Barrier Function and Polarizes Adaptive T Cell Expansion Contributing to Neurocognitive Damage in Experimental Cirrhosis

Experiments in animalsMechanisms

Biomedicine & Pharmacotherapy24 Oct

PAD inhibition downregulates the cellular fibrotic behavior of senescent myofibroblasts derived from dilated cardiomyopathy

Experiments in cellsMechanisms

The Journals of Gerontology, Series A27 Aug

Lumican Is Both a Novel Risk Factor and Potential Plasma Biomarker for Vascular Aging, Capable of Promoting Vascular Smooth Cells Senescence Through Interacting With Integrin α2β1

Study in peopleMechanisms

JCI Insight23 May

Methionine as a regulator of bone remodeling with fasting

Trial in peopleInterventions

Current Issues in Molecular Biology27 Mar

Effects of Blood-Derived Products on Cellular Senescence and Inflammatory Response: A Study on Skin Rejuvenation

Experiments in human cellsSkin

Frontiers in Physiology15 Mar

miR-146a is a critical target associated with multiple biological pathways of skin aging

Experiments in human cellsSkin