Cognitive frailty
Biomarker1 paper1 finding
- Humans1
Associations
1Type 2 diabetes
downin humans1OR 0.66
1 study
Type 2 diabetes
downin humans1OR 0.66
Cognitive frailty lowers the risk of type 2 diabetes in humans (OR 0.66, 95% CI 0.59-0.74).
Humansfavourable vs unfavourable dynamicsn = 23,458
Favourable cognitive frailty trends linked to lower diabetes risk · Diabetes research and clinical practice · 4 Oct 2026
Latest
4Favourable cognitive frailty trends linked to lower diabetes risk
Favourable cognitive frailty dynamics were linked to lower odds of next-wave diabetes compared with unfavourable dynamics (OR 0.66).Favourable cognitive frailty dynamics were linked to lower odds of next-wave diabetes compared with unfavourable dynamics (OR 0.66).
Early cognitive frailty can reverse in rural older adults
In rural older adults, transition intensity from reversible cognitive frailty was 0.429 toward cognitive impairment alone and 0.291 toward physical…In rural older adults, transition intensity from reversible cognitive frailty was 0.429 toward cognitive impairment alone and 0.291 toward physical frailty, versus 0.224 toward further deterioration.
Persistent depression links to faster frailty accumulation
Persistent high depressive symptoms predicted faster non-cognitive frailty accumulation at 1.42 × 10-3/year and elevated odds of incident frailty…Persistent high depressive symptoms predicted faster non-cognitive frailty accumulation at 1.42 × 10-3/year and elevated odds of incident frailty across three aging cohorts.